Organizations that want to get involved in the transformation of their businesses, as a result of digital impact and innovation, will have to quickly rethink their processes and how to manage their portfolios of projects and initiatives. Transformational initiatives in general, and digital initiatives in particular, require a deep immersion in processes and data. And they are based on a core process management skill set. The agile articulation of these transformations, managed from an evolved Transformation Office, are essential aspects to consider to attend to the impacts of said initiatives. The Transformation Office, with a broader perspective than the traditional PMO –Project Management Office-, integrates all the dimensions and capacities necessary to manage and govern complex transformation processes.